Principal Proposed Uses
What is Lobelia Used for Today?
1 Dwoskin LP, Crooks PA. A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse. Biochem Pharmacol . 2002;63:89–98.
2 Miller DK, Crooks PA, Teng L, et al. Lobeline inhibits the neurochemical and behavioral effects of amphetamine. J Pharmacol Exp Ther . 2001;296:1023–34.
3 Harrod SB, Dwoskin LP, Crooks PA, Klebaur JE, Bardo MT. Lobeline attenuates d-methamphetamine self-administration in rats. J Pharmacol Exp Ther . 2001;298:172–9.
4 Davison GC, Rosen RC. Lobeline and reduction of cigarette smoking. Psychol Rep . 1972;31:443–56.
5 Marlin DJ, Roberts CA, Schroter RC, Lekeux P. Respiratory responses of mature horses to intravenous lobeline bolus. Equine Vet J . 2000;32:200–7.
6 Decker MW, Majchrzak MJ, Arneric SP. Effects of lobeline, a nicotinic receptor agonist, on learning and memory. Pharmacol Biochem Behav . 1993;45:571–6.
7 Hamann SR, Martin WR. Hyperalgesic and analgesic actions of morphine, U50-488, naltrexone, and (-)-lobeline in the rat brainstem. Pharmacol Biochem Behav . 1994;47:197–201.
8 Subarnas A, Tadano T, Oshima Y, Kisara K, Ohizumi Y. Pharmacological properties of beta-amyrin palmitate, a novel centrally acting compound, isolated from Lobelia inflata leaves. J Pharm Pharmacol . 1993;45:545–50.
9 Subarnas A, Tadano T, Nakahata N, et al. A possible mechanism of antidepressant activity of beta-amyrin palmitate isolated from Lobelia inflata leaves in the forced swimming test. Life Sci . 1993;52:289–96.
10 Subarnas A, Oshima Y, Sidik, Ohizumi Y. An antidepressant principle of Lobelia inflata L. (Campanulaceae). JPharm Sci . 1992;81:620–1.
11 Bergner P. Is lobelia toxic? Medical Herbalism . 1998;10:1,15–32.
12 Wright IS, Littauer D. Lobeline sulfate: its pharmacology and use in the treatment of the tobacoo habit. JAMA . 1937;109:649–654.
13 Felter HW, Lloyd JU. King’s American Dispensatory , 18th ed. Sandy, OR: Eclectic Medical Publications, 1898, 1983; 1199–205.
14 Raj H, Bakshi GS, Tiwari RR, Anand A, Paintal AS. How does lobeline injected intravenously produce a cough? Respir Physiol Neurobiol . 2005;145:79–90.
15 Butler JE, Anand A, Crawford MR, et al. Changes in respiratory sensations induced by lobeline after human bilateral lung transplantation. J Physiol . 2001;534(Pt. 2):583–93.
16 Raj H, Singh VK, Anand A, Paintal AS. Sensory origin of lobeline-induced sensations: a correlative study in man and cat. J Physiol. 1995;482(pt 1):235–46.
- Reviewer: EBSCO CAM Review Board
- Review Date: 07/2012 -
- Update Date: 07/25/2012 -